Therapeutic Potential Of Cannabidiol In Managing Chronic Pain

If you ask healthcare providers about the most challenging condition to treat, chronic pain is mentioned frequently. By its nature, chronic pain is a complex and multidimensional experience. Pain perception is affected by our unique biology, our mood, our social environment, and past experiences. If you or a loved one is suffering from chronic pain, you already know the heavy burden.

Given the ongoing challenges of chronic pain management coupled with the consequences of the opioid epidemic, pain management practitioners and their patients are searching for effective and safer alternatives to opioids to alleviate pain.

Do you know CBD oil may reduce: pain, inflammation, and overall discomfort related to a variety of health conditions? If you read about various ways to treat pain, you will see the research on CBD products and pain management has been promising.

Some people with chronic pain use topical CBD products, in particular CBD oil, to manage their symptoms. CBD oil India online can offer an alternative for people who have chronic pain and rely on medications, such as opioids, that can be habit-forming and cause more side effects. However, more research is needed to verify the pain-relieving benefits of CBD oil and other products.

What’s the thinking behind using cannabis for chronic pain?

CBD is emerging as a promising pharmaceutical agent to treat pain, inflammation, seizures, and anxiety without the psychoactive effects of THC. Our understanding of the role of CBD in pain management continues to evolve, and evidence from animal studies has shown that CBD exerts its pain-relieving effects through its various interactions and modulation of the endocannabinoid, inflammatory, and nociceptive (pain sensing) systems. The endocannabinoid system consists of cannabinoid receptors that interact with our own naturally occurring cannabinoids. This system is involved in regulating many functions in the body, including metabolism and appetite, mood and anxiety, and pain perception. Also Read: Medicinal Cannabis for Treatment of Chronic Pain

How does CBD function for chronic pain relief?

Everyone has a cell-signalling system known as the endocannabinoid system (ECS).

Some researchers think that CBD interacts with a core component of the ECS — endocannabinoid receptors in your brain and immune system.

Receptors are tiny proteins attached to your cells. They receive signals, mostly chemical ones, from different stimuli and help your cells respond.

This response creates anti-inflammatory and pain-relieving effects that help with pain management. This means that CBD oil and other products may benefit people with chronic pain, such as chronic back pain.

One 2018 review assessed how well CBD works to relieve chronic pain. The review looked at studies conducted between 1975 and March 2018. These studies examined various types of pain, including:

• cancer pain

• neuropathic pain

• fibromyalgia

Based on these studies, researchers concluded that CBD was effective in overall pain management and didn’t cause negative side effects.

CBD for cancer treatment relief

Some people with cancer also use CBD oil India online. Research on mice has shown that CBD can lead to the shrinking of cancerous tumors. However, most studies in humans have investigated the role of CBD in managing pain related to cancer and cancer treatment.

The National Cancer Institute (NCI)Trusted Source has pointed to CBD as a possible option for reducing chemotherapy side effects, such as:

• Pain

• vomiting

• lack of appetite

In a 2010 study on cancer-related pain, study subjects received oral sprays of a combination THC-CBD extract. The THC-CBD extract was used in conjunction with opioids. This study revealed that using the extract provided more effective pain relief than using the opioids alone.

A 2013 study on THC and THC-CBD oral sprays had a similar finding. Many researchers from the 2010 study worked on this study as well. More evidence is still needed.

CBD for migraine pain relief

Studies on CBD and migraine are limited. The studies that currently exist also look at CBD when it’s paired with THC, not when it’s used alone.

However, results from a 2017 study indicate that CBD and THC can lead to less acute pain and less intense pain for people with migraine.

In this two-phase study, some participants took a combination of two compounds. One compound contained 9 percent CBD and almost no THC. The other compound contained 19 percent THC. Doses were taken orally.

In phase I, there was no effect on pain when the doses were under 100 mg. When the doses were increased to 200 mg, acute pain fell by 55 percent.

In phase II, participants who received the combination of CBD and THC compounds saw the frequency of their migraine attacks fall by 40.4 percent. The daily dose was 200 mg.

The combination of compounds was slightly more effective than 25 mg of amitriptyline, a tricyclic antidepressant. Amitriptyline reduced migraine attacks by 40.1 percent in study participants.

Participants with cluster headaches also found pain relief with the combination of cbd oil India buy online and THC compounds, but only if they’d had a childhood history of migraine. Also Read: Does CBD oil work for migraine? Benefits and risks