Treat Parkinson's Disease With CBD Oil

Parkinson’s is a progressive, degenerative medical condition that affects the basal ganglia of the brain, slowly damaging movement and muscle control and often leading to dementia. There is no cure for Parkinson’s, though treatment may work for a short time. However, it has unpleasant side effects and may eventually stop working. This means that even with treatment, symptoms tend to get worse with time. Parkinson’s drugs usually ease symptoms for 3 to 6 years. However, they become less effective after that period.

A person may also need additional medications to manage symptoms such as erectile dysfunction, fatigue, depression, or mood changes. The lack of a cure and the challenges of finding effective treatment both help explain why some people with the disease buy cbd oil online.

What does the research say?

A 2019 paper proposes that cannabinoids such as CBD oil may help reduce neurological inflammation, which could treat Parkinson’s. More research needs to test this claim.

A 2020 study tested Epidiolex, an FDA-approved CBD drug for seizures, for Parkinson’s. Of 13 participants, three quit the study because of side effects. The remaining 10 experienced improvements in their Parkinson’s disease symptoms. However, five of 13 participants developed elevated liver enzymes — a side effect the researchers attribute to the high dose of the drug.

While these results are promising, the sample size was very small, and there was no placebo to compare results to.

A 2019 paper reviewed prior studies on CBD and Parkinson’s. The study included four randomized controlled trials. However, just one of these trials showed improvements in Parkinson’s symptoms among participants.

In seven preclinical models of Parkinson’s disease, six studies suggested CBD could offer neuroprotective benefits.

In three additional trials of CBD and Parkinson’s — one randomized controlled trial, one case series, and one open-label study — participants tolerated CBD well. Additionally, all three studies reported improvements in non-motor Parkinson’s symptoms. Non-motor symptoms can be more difficult to treat with standard Parkinson’s treatment.

Once again, however, these studies involved only small groups of participants and were short in length.

Can you use Canabis to treat Parkinson’s?

Cannabis usually refers to products containing tetrahydrocannabinol (THC), which is the psychoactive compound found in cannabis.

Participants generally reported improvement in symptoms, including:

• reductions in pain and muscle cramps

• reductions in tremors

• reductions in anxiety and depression

• Participants also reported that cannabis had few side effects.

How does CBD oil treat Parkinson’s?

Parkinson’s disease clinically manifests as dyskinesia (impairment of movement), resting tremor, bradykinesia (slow movements), dystonia (stiffness of muscles including facial muscles), a stooped posture, drooling, sexual and urinary dysfunction, and in some cases psychiatric symptoms including psychosis, dementia and depression.

The brain has a rich expression of cannabinoid receptors in various sites, such as the G-protein coupled receptor GPR6 within the basal ganglia (a key part of the brain affected by Parkinson’s). Studies investigating the oral intake of CBD oil (and smoking cannabis) in the treatment of Parkinsonian symptoms have observed generally positive results.

One observational study reported rapid alleviation of Parkinsonian symptoms (including bradykinesia and tremor) upon cannabis smoke inhalation (CBD + THC) in around 79% of patients (out of 28). In another study, 56% of a small cohort of patients showed improvement in mood and sleep issues

In a larger study of 339 Czech patients with Parkinson’s who were routinely using cannabis leaves orally (CBD + THC), there was significant improvement in resting tremors, bradykinesia and rigidity with little or no side effects overall. Symptoms were ameliorated particularly in patients who had been using cannabis for over 3 or more months.

Studies focusing on the use of CBD oil alone show mixed results. One study showed that oral CBD oil reduced psychotic symptoms in Parkinson’s patients, but with little effect on dyskinesia. However, it produced generic improvement in physical state as well as in insomnia-related issues. Larger studies are necessary to confirm these findings, however, as these studies had a relatively small sample size (<20).

However, some studies suggest CBD may have some positive effects, especially when it comes to nonmotor symptoms, such as depression, anxiety, and sleep disorders.

Pain: A small study of 22 individuals with Parkinson’s found that using cannabis helped improve pain. However, this study was conducted with medical marijuana, which contains both CBD and THC. But animal studiesTrusted Source have suggested CBD alone has benefits for reducing pain and inflammation, two factors that can affect people with PD regularly.

Tremors: Some of the most common treatments for Parkinson’s disease can cause medicine-related tremors or uncontrolled muscle movements. Treatment with the medicine won’t make it better — and it could make it worse.

As a possible solution, an older, smaller study has suggested that CBD may be able to help ease these muscle movements.

Psychosis: Psychosis is a possible complication of Parkinson’s disease. It can cause hallucinations, delirium, and delusions, and it’s more common in people in the later stages of the disease. In fact, up to 50 percent of people with PD experience this complication.

While medications are available to treat Parkinson’s psychosis, some people have wondered if CBD might be beneficial.

One small 2009 study in individuals with Parkinson’s disease and psychotic symptoms found that the compound did reduce the severity of symptoms. It also didn’t cause any adverse effects.

Sleep: Sleep disruption and a lack of quality sleep is a serious concern for people with Parkinson’s disease. Vivid dreams or nightmares, as well as movement during sleep, is common. Studies have found that both cannabis and CBD alone might helpTrusted Source with sleep disturbances.

CBD as a prevention for Parkinson’s

Researchers have found that those buy cbd oil online may be able to help prevent Parkinson’s disease, but currently, research has only been done in animals.

Plus, the research suggests CBD can do nothing to help treat PD once it begins. Based on this, it may only be useful as a preventive measure.

But human studies that analyzed whether CBD could help prevent Parkinson’s didn’t return significant results. More research is needed to understand why the compound might protect animals’ brains but — so far as we can tell — not human brains.

What is the ideal dosage of CBD to treat Parkinson?

There are no standard medical guidelines for using CBD for Parkinson’s because CBD is not a prescription drug. Studies of CBD often use dosages of 150–400 milligrams per day.

People who want to try CBD should start with a low dosage, then gradually increase the dosage only if they experience no side effects.

Before trying CBD, contact a doctor about the risks and benefits, as well as any potential drug interactions.

So we are saying,

A number of studies suggest that there may be some benefits of CBD for Parkinson’s. The problem is that most of these studies are small, low quality, or animal studies rather than human ones. And the studies that have already been done, their anecdotal evidence suggests that cannabidiol (CBD) oil for Parkinson’s may help with some symptoms. People who want to try CBD should talk with a CBD-knowledgeable physician and start with a low dosage. They should also discuss options for trying CBD while continuing standard Parkinson’s treatments. However, there is no conclusive research showing CBDs effectiveness in treating Parkinson’s or its symptoms. Hence, it is suggested that you take an online medical consultation with a Hempstrol’s team of experts before you buy Cannabidiol oil and they will take into account your current medical condition before suggesting a dosage.