Can CBD Oil Cure Neurodegenerative Disorders?

Do you know Millions of people worldwide are affected by neurodegenerative disorders? 

For those who don’t know much, the term "neurodegenerative diseases" refers to any ailment that primarily affects neurons in the brain. It affects the brain as well as the nerves that run throughout your body and spinal cord. Neurodegenerative disorders occur when nerve cells, or neurons, in the brain and peripheral nervous system, cease to function and die. They are defined by a progressive loss of nerve cell structure and function in the central and peripheral nervous systems. Neurons are the nervous system's living wires, which include the brain and spinal cord.

A person's risk of developing a neurodegenerative disease is increased by a number of factors. Genetic mutations, traumatic brain injury, and environmental variables such as pesticides and heavy metals are examples of these. The most persistent risk factor for the development of a neurodegenerative illness, however, is age. The symptoms of this condition can be severe at times, even leading to death. Among the most difficult signs are:

• Impaired memory and cognition

• Problems with mobility

• Weakness

• Paralysis

• Breathing problems

• Impaired Heart Function 

It can result in a gradual loss of motor and/or cognitive functions, which can emerge as one of several types of neurodegenerative disorders. The two most prevalent NDs are Alzheimer's disease (AD) and Parkinson's disease (PD), with other forms including amyotrophic lateral sclerosis (ALS), Huntington's disease, spinal muscular atrophy, motor neuron disorders, prion diseases, and spinocerebellar ataxia. None is curable, thus treatment is symptomatic. The consequences for sufferers and their loved ones are catastrophic. These disorders are classed as "sudden onset," which refers to disorders induced by brain or spinal cord damage; "intermittent conditions," which include epilepsy and multiple sclerosis (in its early stages); and "progressive ailments," which worsen with time, such as Parkinson's. 

Although various treatments have been shown to alleviate some of the physical or mental symptoms associated with neurodegenerative disorders, halting or curing their progression is presently not viable. Furthermore, the risk of getting a neurodegenerative disease rises considerably with age.

Because no genuine treatment has yet been discovered, and because the number of people affected by neurodegenerative illnesses around the world is expected to rise, finding strategies to cure or at least slow the advancement of these diseases is critical. Because of their neuroactive and high antioxidant effects, cbd oil India or cannabis has recently been investigated as a viable pharmacological aid for treating NDs. Emerging preclinical research studies have shown that CBD has neuroprotective effects due to its antioxidant and anti-inflammatory qualities, suggesting that it could be used to treat a variety of neurodegenerative illnesses.

Cannabinoids are well known for their anti-inflammatory and neuroprotective effects. Their anti-oxidative and neuroprotective qualities have been shown in studies to have the ability to slow the progression of neurodegenerative illnesses. As a result, experts believe they may be effective in the prevention, treatment, and eventual reversal of neurodegenerative illnesses.

Why is CBD cannabis a popular alternative for symptom and issue relief in neurodegenerative diseases? 

First and foremost, it is worth noting that cbd oil India is fully natural and has no (severe) adverse effects. Another key element is the rising quantity of scientific studies confirming CBD's numerous beneficial effects. Every year, additional research is conducted (some of it quite promising), and scientists believe that we are on the verge of numerous breakthroughs in understanding and treating neurodegenerative illnesses.

Due to its broad spectrum of pharmacological properties (e.g., neuroprotective, antioxidant, and anti-inflammatory effects), CBD is recognized as a multipurpose drug for the treatment of a number of neurodegenerative disorders, including neoplasms of the nervous system, according to studies.

CBD lowers oxidative stress in the body and the brain: Antioxidants are compounds that shield our cells from free radicals and oxidative stress. Free radicals cause undesirable chemical reactions and cell damage in the body, which speeds up aging and can lead to a variety of disorders, including neurological diseases. CBD, like other antioxidants, has been shown in studies to disrupt the chain reactions of free radicals, scavenge them, or transform them into less active forms. 

Reduces insomnia and stress: Both stress and lack of sleep lead to oxidative stress in the brain and impede the body from recharging its batteries and rebuilding its cells. This is especially important in the case of neurodegenerative illnesses, as the body needs as much rest as possible. Furthermore, sleeplessness is one of the most common symptoms of Parkinson's disease, and it has a substantial impact on patients' quality of life. Adding CBD oil to your routine naturally increases sleep quality and minimizes insomnia.

CBD inhibits inflammatory processes, including those in the brain: Chronic inflammation in the brain appears to be a major contribution to the development of two of the most common neurodegenerative disorders, Alzheimer's and Parkinson's. CBD cannabinoid has an extraordinary potential to modulate the immune system and, as a result, inflammatory processes in the human body. In fact, immune system abnormalities are frequently the primary causes of chronic inflammation in the body (together with lifestyle and some external variables). CBD binds to CB2 receptors in the body, which are linked to the immune system, and so acts directly on the latter, reducing its overactivity and inflammatory processes. 

How does CBD work with CNS to protect you from Neurodegenerative illness?

Cannabinoids interact with the body's endocannabinoid system (ECS). They exert their effects on the human body through this system. One should know that the ECS is found in all animals and regulates a variety of bodily functions including sleep, mood, hunger, hormone synthesis, and immunological and neurological system responses. It contributes to the body's homeostasis by regulating these functions.

There is evidence that cannabis has neuroprotective properties. The study of how brain receptors can help persons with neurodegenerative illnesses is still ongoing.

According to a study conducted by the American Academy of Neurology, certain cannabinoids are beneficial or may be effective in the treatment of painful spasms, spasticity, and central discomfort associated with multiple sclerosis. CBD oil may also be useful in lowering inflammation, which can exacerbate neurological symptoms. More research is needed, however, to completely understand how cannabinoids can treat, prevent, or reverse neurodegenerative illnesses.

How does CBD help with the following illness-caused neurodegenerative diseases?

1. Multiple Sclerosis (MS): CBD has been shown in 2018 research to decrease muscular stiffness and pain levels associated with multiple sclerosis by lowering inflammation levels. The substance has been shown to reduce weariness associated with neurological illness by lowering chronic peripheral inflammation, which frequently results in vagus nerve hyperactivity. It is possible that using CBD oil for neurological disorders can lead to improvements in the mobility of people with multiple sclerosis based on indirect evidence of the compound's potential to alleviate fatigue-causing symptoms.

2. Parkinson's: Protection of the neuron is vital to dopamine protection and do you know neuronal degeneration is one of the early symptoms of Parkinson's disease? Parkinson's disease produces dopamine depletion, which weakens the brain's basal ganglia. This has a devastating effect on a Parkinson's patient's movement and mobility. CBD oil can help fight neuronal damage, regulate dopamine production, and slow the progression of Parkinson's disease. CB1 receptors are abundant in this area of the nervous system. CBD and tetrahydrocannabinol (THC) are cannabinoids that bind to these receptors. This binding aids in the relief of symptoms associated with dopamine insufficiency.

3. ALS: Neurodegenerative illnesses are all caused by damage to the central nervous system, although their symptoms are all different. Amyotrophic lateral sclerosis (ALS) progresses quickly, and patients frequently only live for 3 to 5 years from the onset of symptoms. In contrast, the progression of Alzheimer's or Parkinson's disease is usually sluggish, and individuals might live for many years after being diagnosed. Cannabis has long been recognized for its ability to decrease the course of ALS and provide relief from its related symptoms. Cannabinoids, such as THC and cannabinol (CBN), have been shown in preclinical investigations to have anti-inflammatory, neuroprotective, and anti-oxidative properties. CBD oil's capacity to aid in stabilizing motor function, reduce systemic inflammation, relieve pain, and, in some situations, promote neuroregeneration makes it an intriguing potential treatment for these disorders. Numerous animal studies have demonstrated that cannabis can delay the onset of ALS, prolong neuronal life, and reduce the disease's course. 

4. Alzheimer: According to a 2019 study, CBD's neuroprotective and anti-inflammatory properties may help to reduce the severity of some Alzheimer's symptoms. Because Alzheimer's symptoms are aggravated when the brain's immune cells are unable to clear disruptive blockages, cannabidiol may be able to reduce the disease's impact by reducing inflammation in the affected areas. CBD has been shown in studies to be capable of repairing cognitive impairments in mice with a genetic vulnerability to Alzheimer's disease due to its neuroprotective, anti-inflammatory, and anti-oxidative properties. One of the most prominent symptoms of Alzheimer's disease is a steady progression of brain shrinkage, which causes cognitive impairment and the breakdown of neuronal networks. CBD oil has been shown in several animal experiments to not only prevent brain atrophy, but also to increase neurogenesis, or the rebuilding of brain cells.

5. Huntington's disease: It is a hereditary disorder that causes brain cell death. Minor changes in mood or mental functioning are the initial signs, followed by a loss of coordination and balance. Unfortunately, there has been research on the use of CBD to treat Huntington's disease and mobility issues. However, because CBD has anti-inflammatory properties, it may be able to treat certain symptoms of Huntington's disease in the same way that it does for Parkinson's and Alzheimer's.

As a result, 

There are over 600 neurological illnesses due to the complexity of the human body. However, the focus of CBD for neurological illnesses has been limited to the most common forms, which include: Migraines. Epilepsy, Vascular diseases (typically caused by blood vessel obstructions), Infectious diseases (such as Lyme disease, syphilis, TB, and others), Degenerative disorders (for example, dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, Multiple Sclerosis, and so on), Movement disorders (such as ataxia, dystonia, and others), Muscular dystrophy and myositis are examples of neuromuscular disorders. These illnesses can present with a variety of symptoms, but they are often difficult to diagnose without the assistance of a professional. We advocate doing so before thinking about or inquiring about CBD for neurological problems.

Cannabis use has the potential to be an effective strategy for improving the lives of persons with NDs. While getting cannabidiol oil online in India is far from a cure, it may be able to rebuild and protect neurons in the brain while also providing symptom alleviation without the same adverse effects.

Also Read: Cannabidiol for neurodegenerative disorders: A comprehensive review